The report includes the prevalence of musculoskeletal disorders, with osteoarthritis affecting over 500 million people globally. It covers market adoption rates of bone graft substitutes, Visco supplements, and stem cell therapies, highlighting their increasing demand due to minimally invasive procedures. The report examines healthcare expenditure trends, showing a rise in orthopedic treatment costs and insurance reimbursement patterns across key regions. It also presents clinical trial data and R&D investments, showcasing innovation in biologic implants and regenerative medicine advancements.