Cannabis sativa, a herbal medication, contains cannabinoids like THC and CBD that interact with brain and nerve receptors. While THC and CBD are the most studied, the plant includes around 100 cannabinoids concentrated in its leaves and flowers. Cannabis is often used recreationally and to manage conditions like multiple sclerosis (MS) and nerve pain, with moderate evidence supporting its effectiveness in alleviating symptoms like muscle spasms and nerve discomfort. However, claims about its efficacy for other conditions, such as migraines or COVID-19, lack strong scientific backing. Cannabis differs from hemp, which contains minimal THC (less than 0.3%) and is legal under federal law in the U.S., whereas cannabis remains federally prohibited but is legalized in some states. Side effects of cannabis can include breathing problems, cardiovascular risks, and dependence when inhaled or consumed orally. High doses, especially in edibles, may cause severe adverse effects like cannabinoid hyperemesis syndrome (CHS), marked by uncontrollable nausea and vomiting.