Danger of Mixing Gabapentin (Neurontin) and Tramadol ( Ultram)
Combining Gabapentin (Neurontin) and Tramadol (Ultram) results in sedation, dizziness, confusion, respiratory depression, and seizures. Tramadol decreases the seizure threshold, elevating risks when used with Gabapentin. The combination can also result in serotonin syndrome and poor coordination. Always consult a physician prior to using these medications together to prevent serious health complications.