Addiction has wide-ranging and serious impacts. Alcohol and drugs have a huge variety of effects on people. Although everyone reacts differently, “COMPULSION” to drugs is a predicament that all drug users can relate to. In actuality, all medicines have a detrimental effect on the brain. The “CRAVING” for the substance is a significant psychological impact of drug addiction and alcoholism. Drugs enter the bloodstream one way or another whether they are swallowed, breathed, or administered intravenously. The “Blood-Brain Barrier,” a remarkable membrane that shields the brain, is caused here. This is when it becomes harmful to your immune system. Drug addiction is a result of how the drug affects the brain and the effects of various medications on the body vary. For instance, Alcohol affects the brain’s GABA, glutamate, and dopamine neurotransmitters on three different levels while stimulants are known to excite the body’s system.