Huminsulin Injection is a recombinant human insulin that is biologically identical to insulin naturally produced by the pancreas. Manufactured using rDNA technology, it has become one of the cornerstones of diabetes therapy. Unlike older forms of insulin derived from animal sources, Huminsulin provides a more consistent and safer treatment experience, making it highly preferable in both hospital and home-care settings. Available in several formulations—Huminsulin R (Regular insulin), Huminsulin N (NPH insulin), and Huminsulin 30/70 (Premixed)—it covers various patient needs, from postprandial control to basal insulin support. ________________________________________ 2. Composition and Available Variants Each variant of Huminsulin has been meticulously designed to offer specific pharmacological benefits: • Huminsulin R (Regular): A short-acting insulin that begins to work within 30 minutes and lasts up to 8 hours. Ideal for mealtime glucose control. • Huminsulin N (NPH): An intermediate-acting insulin that starts in 1-2 hours and lasts up to 18 hours. Used for basal insulin support. • Huminsulin 30/70: A premixed insulin containing 30% regular and 70% NPH, combining rapid and extended glucose control. Each mL of Huminsulin typically contains 100 IU of human insulin, suspended in a sterile, isotonic solution for subcutaneous injection. ________________________________________ 3. Mechanism of Action: How It Works in the Body Understanding the mechanism of action of Huminsulin provides profound insight into why this synthetic insulin is considered a cornerstone in diabetes management. At its core, Huminsulin is designed to function identically to the endogenous insulin produced by the beta cells of the pancreas. It facilitates glucose homeostasis—one of the most crucial metabolic processes in the human body.